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BP15062
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Enmein
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Enmein shows a significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 μg/ml to 8.2 μg/ml.
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BP15063
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Epiberberine chloride
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Epiberberine chloride is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor (IC50s: 1.07, 6.03 and 8.55 μM).
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BP15064
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Epicatechin pentaacetate
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Epicatechin pentaacetate is a phenolic compound from the V. mullaha fruit extracts, the utilization of V. mullaha fruit as functional food with prospective pharmaceutical, nutraceuticals and cosmeceutical properties.
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BP15065
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Ergosta-7,22-dien-3-one
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Ergosta-7,22-dien-3-one shows pro-inflammatory property, it can stimulate nitric oxide production, induce the expression of genes, and induce the production of TLRs, cytokines, chemokines, and cellular adhesion molecules in J774A.1 cells.
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BP15066
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Esculin
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Esculin is a glucoside found in horse chestnuts.
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BP15067
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Esonarimod
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Esonarimod is an antirheumatic drug.
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BP15068
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Ethyl ferulate
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Ethyl ferulate is the alkyl ester derivative of ferulic acid which is a naturally occurring plant product with anti-oxidative, anti-inflammatory, neuroprotective, and antiproliferative activities.
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BP15069
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EX-A5758
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EX-A5758 is a novel putative small molecule nNOS-NOS1AP inhibitor, suppressing inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability.
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BP15070
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Ezetimibe ketone
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Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Ezetimibe is a potent cholesterol absorption inhibitor.Ezetimibe ketone (EZM-K) is a phase-I metabolite of Ezetimibe.
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BP15071
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Fenoprofen calcium dihydrate
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Fenoprofen calcium is a propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.
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BP15072
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Fiboflapon sodium
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Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.
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BP15073
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Firocoxib
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Firocoxib is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.
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BP15074
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Robinin
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Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
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BP15075
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Flavone
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Flavons have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.
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BP15076
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Flunixin meglumine
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Flunixin Meglumin is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.
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BP15077
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2-(Phosphonooxy)benzoic acid
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Fosfosal, used as the anti-inflammatory agent, has the anti-bacterial effect.
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BP15078
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FR 122047 hydrochloride
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FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively.
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BP15079
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FR-188582
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FR-188582 is a highly selective cyclooxygenase (COX)-2 inhibitor (IC50: 17 nM).
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BP15080
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Gardiquimod
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Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells. Gardiquimod is an imidazoquinoline analog and is a TLR7/8 agonist. When used at concentrations below 10 μM, Gardiquimod specifically activates TLR7.
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BP15081
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GB1107
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GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.
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