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BP14982
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Acemetacin
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Acemetacin is a carboxymethyl ester of indometacin. It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin. In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.
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BP14983
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AF 12198 Acetate
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AF 12198 Acetate is a novel low molecular weight antagonist of IL-1
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BP14984
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Agmatine sulfate
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Agmatine sulfate is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.
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BP14985
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BAY-218
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AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist, has an IC50 of 39.9 nM in human cell line.
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BP14986
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Allylthiourea
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Allylthiourea, a metabolic inhibitor, specifically suppresses ammonia oxidation.
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BP14987
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AM103
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AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).
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BP14988
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Amelubant
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Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity. Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes.
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BP14989
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Amtolmetin guacil
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Amtolmetin guacil inhibits prostaglandin synthesis and cyclooxygenase. Amtolmetin guacil has similar NSAID properties like tolmetin with additional analgesic, antipyretic, and gastroprotective properties.
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BP14990
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Raleukin
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Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.
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BP14991
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Angoline
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Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
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BP14992
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2-Ethoxybenzamide
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Anovigam is white or almost-white crystalline powder. Almost odorless. Tasteless. It is widely used as an antipyretic anodyne.
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BP14993
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Aplaviroc
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Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
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BP14994
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APX-115 free base
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APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase （Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
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BP14995
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ARRY-797
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ARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
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BP14996
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AS-2444697
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AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
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BP14997
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Asperuloside
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Asperuloside has anti-inflammatory activity.
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BP14998
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Avatrombopag
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Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platelet production.
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BP14999
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AZD2098
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AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.
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BP15000
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AZD2423
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AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator and it has an IC50 of 1.2 nM for CCR2 Ca2+ flux.
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BP15001
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BAPTA
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BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.
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