Immunology & Inflammation

Immunology is an act of self-protection of the body against infection and invasion by foreign enemies and the exclusion of foreign molecules, including dead cells of the aging self. The immune response is divided into specific and non-specific, and the general term antigen and antibody responses refer to specific immune responses, which require the participation of B cells and T cells. Other immune cells such as macrophages and NK cells mediate non-specific immune responses and are part of the body's natural defense system. A proper immune response can clear pathogens and is beneficial to the organism. However, an excessive immune response can be harmful to the organism itself. Inflammation is one of the results of a violent immune response.

Cat. No.	Product name
BP15082	Ginsenoside Rh3
BP15082	Ginsenoside Rh3 is a natural product extracted from Panax ginseng C. A. Mey. Ginsenoside Rh3 treatment in human retinal cells induces Nrf2 activation.
BP15083	Glabrol
BP15083	Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15uM.
BP15084	Glafenine
BP15084	Glafenine, a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of various origins.
BP15085	D-(+)-Glucono-1,5-lactone
BP15085	Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder.
BP15086	4”-O-Glucosylvitexin
BP15086	Glucosylvitexin inhibits TPO activity.
BP15087	GLX351322
BP15087	GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
BP15088	Guaiacol
BP15088	Guaiacol is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm.
BP15089	GW-406381
BP15089	GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.
BP15090	Hederacolchiside E
BP15090	Hederacolchiside E has antioxidant activity and shows neuroprotective effects in Alzheimer's disease (AD) models via modulating oxidative stress. Hederacolchiside E exhibits inhibition on lipid peroxidation of linoleic acid emulsion. Hederacolchiside E ma
BP15091	Hesperin
BP15091	Hesperin is a bioactive ingredient present in Japanese horseradish (wasabi). It has been shown to be an activator of Nrf2.
BP15092	hnps-PLA Inhibitor
BP15092	Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
BP15093	HTHQ
BP15093	HTHQ, a hydroquinone monoalkyl ether, is an effective anti-oxidative agent. HTHQ is a potent anti-lipid-peroxidative compound and its antioxidation activity to be extremely elevated in biological systems, such as that of liver microsomes via the generation of stable free radicals.
BP15094	3-Methylsalicylic acid
BP15094	Hydroxytoluic Acid is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels.
BP15095	Ibuprofen Lysine
BP15095	Ibuprofen Lysine is a non-steroidal anti-inflammatory drug.
BP15096	IFN alpha-IFNAR-IN-1 hydrochloride
BP15096	IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.
BP15097	Iguratimod
BP15097	Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.
BP15098	IL-15-IN-1
BP15098	IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).
BP15099	IL-17A antagonist 1
BP15099	IL-17A antagonist 1 is an IL-17A antagonist (Kd: 0.66 μM; IC50: 1.14 μM).
BP15100	ETHYL CAFFEATE
BP15100	In vitro, ECF suppressed the differentiation of naive CD4+ T cells into Th1. Furthermore, ECF intensely blocked the transcriptional expression in interferon-γ-related signaling, including IFN-γ, T-bet, STAT1, and STAT4.
BP15101	INCB3344
BP15101	INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.