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BP16141
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Pyr3
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Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM).
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BP16142
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Quinine hydrochloride dihydrate
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Quinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.
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BP16143
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QX-314 bromide
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QX-314 bromide is a blocker of the membrane-impermeable permanently charged sodium channel.
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BP16144
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Rabeprazole Sulfide
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Rabeprazole is an antiulcer drug in the class of proton pump inhibitors.
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BP16145
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Radequinil
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Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).
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BP16146
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Radiprodil
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Radiprodil (RGH-896) is an orally active and selective NMDA NR2B receptors antagonist. It was a potential treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPNP).
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BP16147
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Ralfinamide
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Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
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BP16148
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Ralfinamide mesylate
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Ralfinamide mesylate is an orally available Na+ channel blocker.
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BP16149
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Raxatrigine
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Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
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BP16150
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Rimeporide
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Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
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BP16151
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Rimeporide hydrochloride
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Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.
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BP16152
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RO 4938581
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RO 4938581 is an effective and selective agonist of GABAA α5 inverse (Ki: 4.6 nM for GABAA α5β3γ2a, and shows a lower affinity at α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki, 174, 185, 80 nM, respectively)).
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BP16153
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Rostafuroxin
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Rostafuroxin has been used in trials studying the treatment of Essential Hypertension.
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BP16154
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RQ-00203078
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RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
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BP16155
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Rufinamide
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Rufinamide, a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders.
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BP16156
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RU-TRAAK-2
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RU-TRAAK-2 is a reversible inhibitor of TWIK-related arachidonic acid-stimulated K+ channel with no activity for non-K2P channels including Kv1.2, GIRK2, and Slo1.
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BP16157
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RWJ-51204
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RWJ-51204 is a partial agonist of GABA(A) receptor (Ki: 0.2-2 nM).
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BP16158
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SCH 50911 hydrochloride
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SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).
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BP16159
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SCH 50911
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SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor (IC50: 1.1 μM). SCH 50911 antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow (IC50: 3 μM).
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BP16160
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Selinexor (KPT-330)
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Selinexor (KPT-330) is an orally available, small molecule inhibitor of CRM1 (chromosome region maintenance 1 protein, exportin 1 or XPO1), with potential antineoplastic activity.
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