Purdue Bioscience - SpeciPure

TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growth.

Pack Size	Availability	Price/USD
1 mg	In stock	$ 202
2 mg	In stock	$ 383
4 mg	In stock	$ 508
10 mg	In stock	$ 1029
20 mg	In stock	$ 1584

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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Description	TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growth.
Targets&IC50	Fgr: 0.03 nM , Hck: 160 nM , Lyn: 0.1 nM
CAS No.	1315330-17-6
Chemical Formula	C32H34F3N5O4
Molecular Weight	609.65
Solubility	DMSO: 120 mg/mL (196.84 mM), Need ultrasonic
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

TL02-59

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