Purdue Bioscience - SpeciPure

Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH).

Pack Size	Availability	Price/USD
2 mg	In stock	$ 100
4 mg	In stock	$ 180
8 mg	In stock	$ 255
20 mg	In stock	$ 540
40 mg	In stock	$ 831

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Description	Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH).
Targets&IC50	SIRT1: 21 μM, SIRT3: 67 μM, SIRT2: 10 μM
CAS No.	1011301-29-3
Chemical Formula	C25H35ClN4O2S
Molecular Weight	491.09
Solubility	DMSO: 100 mg/mL (293.75 mM), Need ultrasonic
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

Tenovin-6 Hydrochloride

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