Purdue Bioscience - SpeciPure

Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.

Pack Size	Availability	Price/USD
5 mg	6-8 weeks	$ 134
10 mg	6-8 weeks	$ 227
20 mg	6-8 weeks	$ 385
50 mg	6-8 weeks	$ 762
100 mg	6-8 weeks	$ 1181

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Description	Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.
Targets&IC50	JAK2: 18 nM, JAK1: 11 nM, JAK3: 155 nM
Synonyms	CYT387 sulfate salt
CAS No.	1056636-06-6
Chemical Formula	C23H26N6O10S2
Molecular Weight	610.61
Solubility	DMSO: 6.2 mg/mL (10.15 mM)
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

Momelotinib sulfate

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In vivo Formulation Calculator (Clear solution)

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