Purdue Bioscience - SpeciPure

IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.

Pack Size	Availability	Price/USD
5 mg	In stock	$ 98
10 mg	In stock	$ 166
20 mg	In stock	$ 264
50 mg	In stock	$ 538
100 mg	In stock	$ 817

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Description	IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.
Targets&IC50	CK1: 16 μM, CDK5: 4.5 mM.
In vitro	Cultures of MEFs of di erent genotypes (p53+/+, p53+/7, p537/7) are treated with the inhibitor IC261 in the low micromolar range (1 μM). After 12, 24, 48 hours exposure, the effects of IC261 on cell cycle distribution are measured by flow cytometry.(Only for Reference)
Synonyms	SU-5607
CAS No.	186611-52-9
Chemical Formula	C18H17NO4
Molecular Weight	311.337
Solubility	Ethanol: <1 mg/mL H2O: <1 mg/mL; DMSO: 58 mg/mL (186.3 mM)
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

IC261

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