H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 101 | |
2 mg | In stock | $ 191 | |
4 mg | In stock | $ 289 | |
10 mg | In stock | $ 506 | |
20 mg | In stock | $ 769 |
Description | H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity. |
In vitro | Immunohistochemistry and Western blotting were used to detect FGFR4 expression in ESCC samples and cell lines. Cell counting kit-8, and clonogenic, transwell, flow cytometric, and tumor xenograft in nude mice assays were utilized to determine the effect of blocking FGFR4 in proliferation, invasion, migration, and apoptosis of ESCC cells. |
CAS No. | 1702259-66-2 |
Chemical Formula | C29H34Cl2N8O4 |
Molecular Weight | 629.54 |
Solubility | DMSO: 10 mM |
Storage | Powder: -20°C for 2 years In solvent: -80°C for 1 year |
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