Purdue Bioscience - SpeciPure

Pack Size	Availability	Price/USD
1 mg	In stock	$ 149
2 mg	In stock	$ 253
4 mg	In stock	$ 452
10 mg	In stock	$ 839
20 mg	In stock	$ 1325

Description	CDDO-EA is an activator of the Nrf2/antioxidant response element.
In vitro	In a cell culture model of ALS, CDDO-EA potently activates Nrf2/ARE . CDDO-EA induces apoptosis in A549 lung cancer cells and induces heme oxygenase-1. CDDO-EA is 7-fold more potent than CDDO as a suppressor of the ability of IFN-γ to induce iNOS in RAW264.7 macrophage-like cells.
In vivo	CDDO-EA-treated G93A mice live significantly longer than the control. CDDO-EA increases the life-span from 124.05 days to 144.72 days (16.6%). In CDDO-EA-treated G93A mice, the age of death is 141.4 days and the duration from the age of onset to the age of death is 57.6 days. The age of death from the onset is prolonged by 17.5 days (43%) .
Synonyms	TP319, RTA 405, CDDO ethyl amide
CAS No.	932730-51-3
Chemical Formula	C33H46N2O3
Molecular Weight	518.73
Solubility	DMSO: 30 mg/mL (57.8 mM)
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

IMPORTANT:

Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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CDDO-EA

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