Purdue Bioscience - SpeciPure

ARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.

Pack Size	Availability	Price/USD
2 mg	In stock	$ 153
4 mg	In stock	$ 275
8 mg	In stock	$ 364
20 mg	In stock	$ 706
40 mg	In stock	$ 1129

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Steps:

Drug concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

IMPORTANT:

Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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Mass of a compound required to prepare a solution of known volume and concentration
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Concentration of a solution resulting from a known mass of compound in a specific volume

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Description	ARRY-797 is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.
In vivo	ARRY-797 inhibits the growth of RPMI-8226 Human Multiple Myeloma Cells. ARRY-371797 prevented left ventricular dilatation and deterioration of fractional shortening compared with placebo-treated mice.
Synonyms	ARRY-371797
CAS No.	1036404-17-7
Molecular Weight	N/A
Solubility	DMSO: 55 mg/ml
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

ARRY-797

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In vivo Formulation Calculator (Clear solution)

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