Cell Cycle

Cell cycle is the entire process of cell division from the completion of one division to the end of the next division and is divided into two phases: interphase and division. Life is a continuous process passed from generation to generation and is therefore a process of constant renewal and starting from scratch. Thus, it is a process of constant renewal and starting from scratch. The life of a cell begins with the division of its parent cell and ends with the formation of its daughter cells, or the death of the cell itself. Usually, the formation of daughter cells is considered to mark the end of cell division. The cell cycle is the process from the formation of daughter cells at one cell division to the formation of daughter cells at the next cell division. During this process, the genetic material of the cell is copied and distributed equally to the two daughter cells.

Cat. No.	Product name
BP13029	Atuveciclib S-Enantiomer
BP13029	Atuveciclib (BAY-1143572) S-enantiomer is a potent and selective CDK9 inhibitor (IC50: 16 nM for CDK9/CycT1).
BP13030	Atuveciclib Racemate
BP13030	Atuveciclib Racemate is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
BP13031	AUNP-12 acetate
BP13031	AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition to immune activation and antitumor activity.
BP13032	Aurora B inhibitor 1
BP13032	Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor, has a Ki value of <0.010 uM.
BP13033	Aurora inhibitor 1
BP13033	Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).
BP13034	Aurora kinase inhibitor-2
BP13034	Aurora Kinase Inhibitor II is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).
BP13035	Aurora kinase inhibitor-3
BP13035	Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.
BP13036	AZ1495
BP13036	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffuse large B-cell lymphoma (DLBCL).
BP13037	AZ191
BP13037	AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.
BP13038	ROCK-IN-2
BP13038	Azaindole 1 is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
BP13039	AZD4573
BP13039	AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
BP13040	AZD-5438
BP13040	AZD5438 is an effective inhibitor of CDK, for CDK1(IC50=16 nM), CDK2(IC50=6 nM), CDK9(IC50=20 nM).
BP13041	AZD-5597
BP13041	AZD-5597 is a potent imidazole pyrimidine amide CDK inhibitor.
BP13042	AZD-7762
BP13042	AZD7762, an effective and specific inhibitor of Chk1（IC50=5 nM）, is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck.
BP13043	AZ-Dyrk1B-33
BP13043	AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
BP13044	Azelaic acid
BP13044	Azelaic acid is bactericidal against Propionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic Acid is a naturally occurring dicarboxylic acid produced by Malassezia furfur and found in whole grain cereals, rye, barley and animal products. Azelaic acid possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. Azelaic acid exerts its keratolytic and comedolytic effects by reducing the thickness of the stratum corneum and decreasing the number of keratohyalin granules by reducing the amount and distribution of filaggrin in epidermal layers. Azelaic acid also possesses a direct anti-inflammatory effect due to its scavenger activity of free oxygen radical. This drug is used topically to reduce inflammation associated with acne and rosacea.
BP13045	BAY-2402234
BP13045	BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.
BP13046	BCH001
BP13046	BCH001 is a specific small-molecule inhibitor of PAPD5.
BP13047	BDP5290
BP13047	BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)
BP13048	Beaucage reagent
BP13048	Beaucage reagent, which is found to be effective in causing DNA cleavage.