Cell Cycle

Cell cycle is the entire process of cell division from the completion of one division to the end of the next division and is divided into two phases: interphase and division. Life is a continuous process passed from generation to generation and is therefore a process of constant renewal and starting from scratch. Thus, it is a process of constant renewal and starting from scratch. The life of a cell begins with the division of its parent cell and ends with the formation of its daughter cells, or the death of the cell itself. Usually, the formation of daughter cells is considered to mark the end of cell division. The cell cycle is the process from the formation of daughter cells at one cell division to the formation of daughter cells at the next cell division. During this process, the genetic material of the cell is copied and distributed equally to the two daughter cells.

Cat. No.	Product name
BP13369	Myriocin
BP13369	Myriocin is a fungal metabolite isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia. Myriocin also is an effective inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin strongly inhibits replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV. It has an IC50 of 3.5 μg/mL for inhibiting HCV infection.
BP13370	N2-Methylguanosine
BP13370	N2-methylguanosine is a modified nucleoside of tRNA that occurs at several specific locations in many tRNA's
BP13371	N6,N6-Dimethyladenosine
BP13371	N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
BP13372	N6-Methyladenine
BP13372	N6-Methyladenine is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DNA functions, including replication, repair, and expression.
BP13373	Narciclasine
BP13373	Narciclasine, a natural product, modulates the Rho/Rho-kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity.
BP13374	Nedaplatin
BP13374	Nedaplatin is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucleophilic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death.
BP13375	Netarsudil Dihydrochloride
BP13375	Netarsudil Dihydrochloride is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
BP13376	N-Ethylmaleimide
BP13376	N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
BP13377	NG 52
BP13377	NG 52 is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.
BP13378	Nimustine Hydrochloride
BP13378	Nimustine has been used in trials studying the treatment of Glioblastoma.
BP13379	NITD-2
BP13379	NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in humans. Neither vaccine nor antiviral therapy is currently available for DENV.
BP13380	NKP-1339
BP13380	NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
BP13381	N-Nitrosodiethylamine
BP13381	N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus.
BP13382	Nolatrexed dihydrochloride
BP13382	Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
BP13383	Nolatrexed
BP13383	Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.
BP13384	Norathyriol
BP13384	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
BP13385	NSAH
BP13385	NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
BP13386	NSC23005 Sodium
BP13386	NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.
BP13387	NSC23005
BP13387	NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).
BP13388	NSC 617145
BP13388	NSC617145 is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.