Cell Cycle

Cell cycle is the entire process of cell division from the completion of one division to the end of the next division and is divided into two phases: interphase and division. Life is a continuous process passed from generation to generation and is therefore a process of constant renewal and starting from scratch. Thus, it is a process of constant renewal and starting from scratch. The life of a cell begins with the division of its parent cell and ends with the formation of its daughter cells, or the death of the cell itself. Usually, the formation of daughter cells is considered to mark the end of cell division. The cell cycle is the process from the formation of daughter cells at one cell division to the formation of daughter cells at the next cell division. During this process, the genetic material of the cell is copied and distributed equally to the two daughter cells.

Cat. No.	Product name
BP13329	LY3177833
BP13329	LY-3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)
BP13330	LY3405105
BP13330	LY3405105 is a novel CDK7 inhibitors.
BP13331	Lysidine
BP13331	Lysidine is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.
BP13332	Madrasin
BP13332	Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
BP13333	Managlinat dialanetil
BP13333	Managlinat dialanetil is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase). It is used for the treatment of type 2 diabetes.
BP13334	Maslinic acid
BP13334	Maslinic acid is a DNA polymerase B inhibitor.
BP13335	MBM-17
BP13335	MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM). It effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.
BP13336	MBM-17S
BP13336	MBM-17S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-17S shows antitumor activities, and no obvious toxicity to mice.MBM-17S is a potent NIMA-related kinase 2 (Nek2) inhibitor, with an IC50 of 3 nM.
BP13337	MBQ-167
BP13337	MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively).
BP13338	MC180295
BP13338	MC180295 is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.
BP13339	BTYNB
BP13339	MDK6620 is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). It disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association
BP13340	MeBIO
BP13340	MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.
BP13341	Men 10376
BP13341	Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.
BP13342	Merestinib dihydrochloride
BP13342	Merestinib dihydrochloride is an effective and orally bioavailable c-Met inhibitor (Ki=2 nM). It has anti-tumor activities and also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM).
BP13343	Metarrestin
BP13343	Metarrestin is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2.
BP13344	Methotrexate metabolite
BP13344	Methotrexate metabolite is the active metabolite of Methotrexate which is a folic acid antagonist. Methotrexate metabolite inhibits parasite growth.
BP13345	Metoprine
BP13345	Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity.
BP13346	Mevociclib
BP13346	Mevociclib is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.
BP13347	MF-094
BP13347	MF-094 is a potent and selective inhibitor of USP30 with IC50 of 120 nM.
BP13348	Adavosertib
BP13348	MK-1775 is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM). It hinders the G2 DNA damage checkpoint.