BP13309
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LDC4297
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LDC4297 is a potent and selective CDK7 inhibitor.
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BP13310
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LDN-192960
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LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
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BP13311
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LDN-91946
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LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
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BP13312
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Lerociclib
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Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 2nM, 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
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BP13313
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Lerociclib dihydrochloride
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Lerociclib dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM and 1 nM for CDK6/CyclinD3 and CDK4/CyclinD1, respectively.
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BP13314
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Folinic acid calcium
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Leucovorin calcium is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.
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BP13315
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Levomefolate calcium
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Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.
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BP13316
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Licorisoflavan A
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Licorisoflavan A shows weak scavenging activity against superoxide anion radical, it and licoricidin have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis.Licorisoflavan A has bactericidal effects on S. mutans UA159 at the concentration of ≥4 g/ml, it can be useful in developing oral hygiene products, such as gargling solutions and dentifrices for preventing dental caries.
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BP13317
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LIMK-IN-22j
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LIMK-IN-22j is an effective and selective inhibitor of LIMK.
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BP13318
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Branaplam
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LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
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BP13319
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Longdaysin
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Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).
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BP13320
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Lusianthridin
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Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling.
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BP13321
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LX7101
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LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
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BP13322
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LY 222306
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LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
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BP13323
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LY 345899
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LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
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BP13324
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LY2334737
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LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
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BP13325
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Abemaciclib methanesulfonate
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LY2835219 is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).
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BP13326
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Abemaciclib
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LY2835219 is an effective and specific CDK4/6 inhibitor (IC50: 2/10 nM).
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BP13327
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LY2880070
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LY2880070 is a new checkpoint kinase 1 (CHK1) inhibitor for cancer therapy.
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BP13328
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LY3143921 hydrate
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LY3143921 hydrate is an orally administered ATP-competitive CDC7 inhibitor.
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