BP13209
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Fadraciclib
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Fadraciclib is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).
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BP13210
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Famciclovir
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Famciclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor. The mechanism of action of famciclovir is as a DNA Polymerase Inhibitor, and DNA Polymerase Inhibitor.
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BP13211
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Fanotaprim
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Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio of 196.
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BP13212
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Favipiravir
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Favipiravir (T-705), an effective and selective RNA-dependent RNA polymerase inhibitor, are applied to treat influenza virus infections.
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BP13213
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Fialuridine
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Fialuridine is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
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BP13214
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FIT-039
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FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
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BP13215
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Flucytosine
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Flucytosine is a pyrimidine compound and a fluorinated cytosine analog exhibiting antifungal activity.
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BP13216
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FMF-04-159-2
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FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET assay, respectively. FMF-04-159-2 is a covalent CDK14 inhibitor.
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BP13217
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FN-1501-propionic acid
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FN-1501-propionic acid and a CRBN ligand have been used to design PROTAC CDK2/9 degrader. FN-1501-propionic acid is a CDK2/9 ligand for PROTAC.
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BP13218
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Folic acid
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Folic acid(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis.
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BP13219
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Folinic Acid Calcium Salt Pentahydrate
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Folinic Acid, a reduced folic acid, is used in combination with other chemotherapeutics.
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BP13220
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Foscarnet sodium
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Foscarnet sodium is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.
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BP13221
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FOY 251
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FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.
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BP13222
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FT671
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FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds to the USP7 catalytic domain (Kd: 65 nM).
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BP13223
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FT827
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FT827 is a selective and covalent inhibitor of ubiquitin-specific protease 7 (USP7) (Ki: 4.2 μM). FT827 binds to the USP7 catalytic domain (apparent Kd: 7.8 μM).
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BP13224
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Ganciclovir
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Ganciclovir is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
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BP13225
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Ganciclovir sodium
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Ganciclovir Sodium is the sodium salt of Ganciclovir with antiviral activity, especially against cytomegalovirus (CMV) and herpes simplex virus type 1 (HSV-1).
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BP13226
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Ganoderic acid DM
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Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.
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BP13227
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Ganoderic acid H
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Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-κB, resulting in the suppression of secretion of uPA.
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BP13228
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Garcinone C
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Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.
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