LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel's gating properties. It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52.
| Description | LRRC52 (leucine-rich repeat-containing protein 52) belongs to the gamma family of the BK channel accessory subunits, which potentially regulate the channel's gating properties. It is dominantly expressed in testis and skeletal muscle, with much lower expression in several other tissues including placenta, kidney, lung, and some glands. LRRC52 has been reported as a Slo3 auxiliary subunit that helps define the specific alkalization dependence of KSper activation. LRRC52 has a calcular molecular weight of 35 kDa. This polyclonal antibody raised against 24-244aa of human LRRC52 reveals a band of 45 kDa, which is consistent with the molecular weight of glycosylated form of LRRC52. |
| Tested Applications | WB: 1:1000; IF: 1:100-1:300; IHC:1:50-1:200 |
| Species Reactivity | Human, Mouse, Rat |
| Host Species/Isotype | Rabbit/IgG |
| Molecular Weight | 45 kDa |
| GenBank | BC132981 |
| Uniprot | Q8N7C0 |
| Concentration | 580 μg/ml |
| Form | Liquid Anti-LRRC52 antibody.gif,Anti-LRRC52 antibody1.gif,Anti-LRRC52 antibody2.gif |
| Storage Instruction | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do Not Aliquot. |
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