MARK2 is also named as EMK1 (ELKL motif kinase 1), Par1b and belongs to the CAMK Ser/Thr protein kinase family. Par1b/MARK2 plays a critical role in neuronal polarity in the process of axon specification from multiple candidate neurites using primary cultures of mammalian hippocampal neurons. It has 16 isoforms produced by alternative promoter usage and alternative splicing with the molecular mass of 77-90kDa and can exsit as a dimer.
| Description | MARK2 is also named as EMK1 (ELKL motif kinase 1), Par1b and belongs to the CAMK Ser/Thr protein kinase family. Par1b/MARK2 plays a critical role in neuronal polarity in the process of axon specification from multiple candidate neurites using primary cultures of mammalian hippocampal neurons. It has 16 isoforms produced by alternative promoter usage and alternative splicing with the molecular mass of 77-90kDa and can exsit as a dimer. |
| Tested Applications | WB: 1:1000; IF: 1:100-1:300; IHC:1:50-1:200 |
| Species Reactivity | Human, Mouse, Rat |
| Host Species/Isotype | Rabbit/IgG |
| Molecular Weight | 77-90 kDa |
| GenBank | BC008771 |
| Uniprot | Q7KZI7 |
| Concentration | 390 μg/ml |
| Form | Liquid |
| Storage Instruction | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do Not Aliquot. |
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