NP118809 is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 123 | |
200 mg | In stock | $ 221 | |
400 mg | In stock | $ 309 | |
1 g | In stock | $ 657 | |
2 g | In stock | $ 1031 |
Description | NP118809 is a potent N-type calcium channel blocker(IC50 : 0.11 μM). |
Targets&IC50 | N-type calcium channel:0.11 μM |
In vitro | NP118809 with a total linker length of 3 carbons (n = 1) and which exhibited approximately a 500-fold increased N-type channel blockade compared to compounds in this series with linkers either shorter (n = 0, 2a) or longer (n = 2 4, (2c e). Examination of the effect of NP118809 on functional L-type calcium channel activity showed that this compound was approximately 111-fold more selective for N-type channels |
Synonyms | 39-1B4 |
CAS No. | 41332-24-5 |
Chemical Formula | C32H32N2O |
Molecular Weight | 460.621 |
Solubility | DMSO: 50 mg/mL (108.55 mM) |
Storage | Powder: -20°C for 2 years In solvent: -80°C for 1 year |
bottom