Purdue Bioscience - SpeciPure

RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.

Pack Size	Availability	Price/USD
1 mg	In stock	$ 193
2 mg	In stock	$ 366
4 mg	In stock	$ 585
10 mg	In stock	$ 945
20 mg	In stock	$ 1417

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Steps:

Drug concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

IMPORTANT:

Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Description	RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
Targets&IC50	PARP5b:10 μM (IC50), PARP11:1 μM (IC50), PARP6:4 μM (IC50), PARP14:<3 nM (IC50), PARP12:5 μM (IC50), PARP16:6 μM (IC50), PARP15:3 μM (IC50), PARP5a:8 μM (IC50), PARP10:1 μM (IC50), PARP7:4 μM (IC50), PARP4:10 μM (IC50), PARP8:20 μM (IC50)
CAS No.	2360851-29-0
Chemical Formula	C19H23FN2O3S
Molecular Weight	378.46
Solubility	DMSO: 10 mM
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

RBN012759

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In vivo Formulation Calculator (Clear solution)

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Molarity Calculator allows you to calculate the

Calculator the dilution required to prepare a stock solution

Calculate the volume of solvent required to reconstitute your vial.

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

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