Purdue Bioscience - SpeciPure

Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

Pack Size	Availability	Price/USD
100 mg	In stock	$ 79
200 mg	In stock	$ 142
400 mg	In stock	$ 187
1 g	In stock	$ 475
2 g	In stock	$ 722

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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Description	Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.
Targets&IC50	NMDA Receptor:0.296 mM, sodium channel:60 μM, nAChR:45.5 μM, 5-HT3:1.7 μM(Kd)
Synonyms	Novocaine HCl, Procaine HCl
CAS No.	51-05-8
Chemical Formula	C13H20N2O2·HCl
Molecular Weight	272.77
Solubility	Ethanol: <1 mg/mL DMSO: 51 mg/mL (187 mM); H2O: 50 mg/mL (183.3 mM)
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

Procaine hydrochloride

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In vivo Formulation Calculator (Clear solution)

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