Purdue Bioscience - SpeciPure

CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.

Pack Size	Availability	Price/USD
1 mg	In stock	$ 200
2 mg	In stock	$ 380
4 mg	In stock	$ 540
10 mg	In stock	$ 1060
20 mg	In stock	$ 1621

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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Description	CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
Targets&IC50	cdk6/cyclin D3:13.9 nM (Ki), Cdk4/cyclin D1:0.6 nM (Ki)
In vitro	CDK4/6-IN-6 (example A94) has IC 50 s of 38.5 nM and 144.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3 using phospho-Rb S795 ELISA assays in JEKO-1 and MV4-1 1 cells.
CAS No.	2380321-51-5
Chemical Formula	C22H27ClFN5O3
Molecular Weight	463.93
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

CDK4/6-IN-6

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Enter the chemical formula of a compound to calculate its molar mass and elemental composition

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