360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 133 | |
2 mg | In stock | $ 226 | |
4 mg | In stock | $ 378 | |
10 mg | In stock | $ 664 | |
20 mg | In stock | $ 1042 |
Description | 360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM). |
Targets&IC50 | Telomerase:300 nM |
In vitro | A549 lung carcinoma cell lines treatment with 5 μM of 360A led to an inhibition of cell proliferation within 11 days of treatmen. Treatment with the newly synthesized dimer (360A)2A led to a comparable antiproliferative effect |
CAS No. | 794458-56-3 |
Chemical Formula | C27H23N5O2 |
Molecular Weight | 449.513 |
Solubility | DMSO: 10 mM |
Storage | Powder: -20°C for 2 years In solvent: -80°C for 1 year |
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