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BP13639
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3α-Hydroxymogrol
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3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle. It is a potent AMPK activator and enhances AMPK phosphorylation.
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BP13638
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3-TYP
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3-TYP is a selective SIRT3 inhibitor.
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BP13620
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AKBA
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3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(5) of 5 m muM.
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BP13637
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3-methyl-1,2-dihydroquinolin-2-one
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3-methyl-1,2-dihydroquinolin-2-one is the first known micromolar inhibitors of the ATAD2 bromodomain.
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BP13636
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3-Methoxybenzamide
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3-Methoxybenzamide is a competitive inhibitor of poly(ADP-ribose) synthetase.
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BP13635
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RGX-202
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3-Guanidinopropionic acid is a creatine analog that alters skeletal muscle energy expenditure. It reduces cellular ATP, creatine, and phosphocreatine levels and stimulates AMP-activated protein kinase (AMPK), activating PPARγ coactivator 1α (PGC-1α).
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BP13634
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3-deazaneplanocin A HCl
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3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor.
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BP13633
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3-Deazaneplanocin A
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3-Deazaneplanocin A (DZNep) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.
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BP13632
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3',6-Disinapoylsucrose
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3, 6'-Disinapoyl sucrose shows the neuroprotective effect and antidepressive activity in rats.
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BP13631
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2-hexyl-4-Pentynoic Acid
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2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.
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BP13630
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5-Fluoro-2'-deoxycytidine
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2'-DEOXY-5-FLUOROCYTIDINE is an inhibitor of DNA methyltransferase (DNMT).
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BP13629
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20-Deoxyingenol 3-angelate
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20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets, it is a protein kinase C (PKC) activator.
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BP13628
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lutidinic acid
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2, 4-Pyridinedicarboxylic acid is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases.
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BP13627
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1-phenoxazin-10-ylethanone
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1-phenoxazin-10-ylethanone is a Pim-2 inhibitor. 1-phenoxazin-10-ylethanone induces apoptosis and autophagic cell death in triple-negative human breast cancer.
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BP13626
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1-Naphthohydroxamic acid
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1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity, But it can induce tubulin acetylation.
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BP13625
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Nudifloramide
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1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
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BP13617
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1,5-Isoquinolinediol
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1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1,5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
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BP13619
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1,4-DPCA
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1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH).
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BP13618
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1,2-Dipalmitoyl-sn-glycerol
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1,2-Dipalmitoyl-sn-glycerol is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.
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BP13616
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[Ala113]-MBP (104-118) acetate
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[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.
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