Cell Cycle

Cell cycle is the entire process of cell division from the completion of one division to the end of the next division and is divided into two phases: interphase and division. Life is a continuous process passed from generation to generation and is therefore a process of constant renewal and starting from scratch. Thus, it is a process of constant renewal and starting from scratch. The life of a cell begins with the division of its parent cell and ends with the formation of its daughter cells, or the death of the cell itself. Usually, the formation of daughter cells is considered to mark the end of cell division. The cell cycle is the process from the formation of daughter cells at one cell division to the formation of daughter cells at the next cell division. During this process, the genetic material of the cell is copied and distributed equally to the two daughter cells.

Cat. No.	Product name
BP13489	SCH900776 (S-isomer)
BP13489	SCH900776 (S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
BP13490	SEL120-34A HCl
BP13490	SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM, respectively), with antitumor activity.
BP13491	SEL120-34A
BP13491	SEL120-34A is a selective, orally available, and ATP-competitive CDK8 inhibitor (IC50s: 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC) with antitumor activity.
BP13492	SEL120-34A monohydrochloride
BP13492	SEL120-34A monohydrochloride is an ATP-competitive and selective inhibitor of CDK8(CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8),has anti-tumor activity.
BP13493	Sempervirine
BP13493	Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA.
BP13494	Senexin A
BP13494	Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.
BP13495	Senexin B
BP13495	Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).
BP13496	SIBA
BP13496	SIBA is a synthetic analogue of SAH, acts as an inhibitor of S-adenosylmethionine-mediated transmethylation. SIBA can interfere with a variety of enzymatic activities in vitro, such as SAH hydrolase, methylthioadenosine phosphorylase and cAMP phosphodiesterase. SIBA reversibly blocks the multiplication of herpes simplex type 1 virus (HSV)
BP13497	Silver sulfadiazine
BP13497	Silver Sulfadiazine is a sulfonamide-based topical agent with antibacterial and antifungal activity.
BP13498	Simurosertib
BP13498	Simurosertib is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM).
BP13499	SJB2-043
BP13499	SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).
BP13500	SL327
BP13500	SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.
BP13501	Saccharin 1-methylimidazole
BP13501	SMI is a general-purpose activator used for DNA and RNA synthesis.
BP13502	SNS-314 Mesylate
BP13502	SNS-314 Mesylate is an effective and specific Aurora A/B/C inhibitor (IC50: 9/31/3 nM). It is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.
BP13503	Sodium Camptothecin
BP13503	Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA .
BP13504	SP-146
BP13504	SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).
BP13505	SP-96
BP13505	SP-96 is a highly effective and selective inhibitor of Aurora B with an IC50 of 0.316 nM. SP-96 shows selective growth inhibition in NCI60 screening, including MDA-MD-468 (GI50=107 nM). SP-96 can be used in triple negative breast cancer studies.
BP13506	SPHINX31
BP13506	SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
BP13507	SR 11302
BP13507	SR 11302 is an inhibitor of activator protein-1 (AP-1).
BP13508	SR15006
BP13508	SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).