BP13429
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PRT4165
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PRT4165 is a potent inhibitor of PRC1-mediated H2A ubiquitylation.
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BP13430
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Puromycin dihydrochloride
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Puromycin hydrochloride is a cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
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BP13431
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Purvalanol B
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Purvalanol B is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)
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BP13432
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Pyridostatin Trihydrochloride
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Pyridostatin hydrochloride is a G-quadruplexe stabilizer, with a Kd of 490 nM.
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BP13433
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Pyridostatin
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Pyridostatin is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres.
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BP13434
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Pyridostatin TFA
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Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2.
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BP13435
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Pyrimethamine
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Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.
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BP13436
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Quinizarin
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Quinizarin is a natural product
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BP13437
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R-10015
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R-10015 is a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket(IC50 of 38 nM for human LIMK1),and a broad-spectrum antiviral compound for HIV infection.
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BP13438
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Rac1 Inhibitor F56, control peptide acetate
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Rac1 Inhibitor F56, control peptide acetate is a control peptide version of Rac1 Inhibitor; comprises residues 45-60 of Rac1 with Trp56 replaced by Phe. Does not affect GEF-Rac1 interaction.
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BP13439
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RAD51-IN-1
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Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.
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BP13440
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RAD51-IN-2
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RAD51-IN-2 is a inhibitor of RAD51.
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BP13441
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Rafoxanide
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Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
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BP13442
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Raltitrexed
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Raltitrexed(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.
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BP13443
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Remdesivir
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Remdesivir is a nucleoside analogue, with effective antiviral activity( EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells)
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BP13444
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GS-443902
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Remdesivir triphosphate is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp) with IC50s of 1.1 µM, 5 µM for RSV RdRp and HCV RdRp, respectively. GS-443902 is the active triphosphate metabolite of Remdesivir.
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BP13445
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RG7800
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RG7800 has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.
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BP13446
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Rho-Kinase-IN-1
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Rho-Kinase-IN-1 is a inhibitor of Rho kinase (ROCK) with Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively
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BP13447
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Rhosin
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Rhosin is an effective and specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction (Kd: ~ 0.4 uM). Rhosin does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin causes cell apoptosis.
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BP13448
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RI-1
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RI-1 is a RAD51 inhibitor (IC50: 5-30 μM).
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