Purdue Bioscience - SpeciPure

BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.

Pack Size	Availability	Price/USD
1 mg	In stock	$ 194
2 mg	In stock	$ 329
4 mg	In stock	$ 552
10 mg	In stock	$ 1116
20 mg	In stock	$ 1785

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)， Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation ：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please refer to the datasheet of our products for more information about solubility. Some auxiliary solubilization methods such as sonication, heating, and vortex shaking may be able to assist in the dissolution of the product.

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Description	BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). BAY-6035 has more than 100-fold selectivity over other histone methyltransferases.
Targets&IC50	SMYD3:88 nM (IC50)
In vitro	BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells with IC50s of 88 and 70 nM, respectively.
CAS No.	2247890-13-5
Chemical Formula	C22H28N4O3
Molecular Weight	396.5
Solubility	DMSO: 100 mg/mL (239.61 mM), Need ultrasonic
Storage	Powder: -20°C for 2 years In solvent: -80°C for 1 year

BAY-6035

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